Ensures through science
General Toxicity studies
Acute toxicity studies in Rats and mice, MTD studies in rat and mice with TK, Dose escalation and range-finding, Non-GLP 4, 7 and 14 day toxicity studies in rat and mice with TK, Sub-chronic & Chronic GLP Toxicity studies
Genotoxicity studies
Ames test, Chromosomal Aberration test (in vitro & in vivo), Micronucleus test (in vitro & in vivo), Gene mutation, HPRT gene mutation,
Other in vitro studies
Cytotoxicity, in vitro skin irritation, in vitro skin corrosion, and in vitro eye irritation.
